Residuals
In the context of least squares (or any other fitting method, e.g. MLE) the residuals are the difference between a model function and the experimental data. In least squares usually the weighted residuals trace is shown:
Rwgt(ti)=D(model parameters,ti)−Dexpiwi
(Dexpi|ti) is the i-th data point of an experimental data set, D(model parameters,ti) is the model equation at the observed points ti.
The weighting factor wi describes the experimental uncertainty of each individual data point. For TCSPC data wi is defined as
wi=√Dexpi
The resudials trace is of importance within any framework concerned with fitting, as the SymPhoTime software or FluoFit.